Fig. 1 · Structure

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Mtb-IN-5

Mtb Inhibitor

Mtb-IN-5 is an isoxazole compound that primarily targets Mycobacterium tuberculosis (Mtb). This inhibitor effectively disrupts Mtb respiration and biofilm formation in macrophage environments, while also enhancing the efficacy of the antibiotic isoniazid against isoniazid-resistant Mtb mutants. Mtb-IN-5 is a valuable tool for research focused on combating tuberculosis and understanding Mtb resistance mechanisms.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2954888-39-0
Applications Mtb Inhibitor
Formula C24H24N2O4S
Molecular Weight 436.52
SMILES
O=C(C1CSC2=C(C3CC3)C(C4=CC(C5=CC=C(C(C)(C)C)C=C5)=NO4)=CC(N21)=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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