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Mtb-IN-8

Mtb Inhibitor

Mtb-IN-8 is a potent inhibitor of Mycobacterium tuberculosis (Mtb) that exhibits minimal inhibitory concentrations (MIC) of 0.03 μg/mL against the H37Rv strain and 0.125-0.06 μg/mL for multidrug-resistant Mtb. This compound is orally active and demonstrates significant efficacy in combating tuberculosis, making it a valuable tool for research on novel anti-tubercular therapies. Its properties facilitate studies on the mechanisms of drug resistance and the development of effective treatment strategies against Mtb infections.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2549199-96-2
Applications	Mtb Inhibitor
Formula	C₁₇H₁₈N₄O₅S
Molecular Weight	390.41
SMILES	COC1=CC=C([C@@H]2C(C(NC(SCCC)=N3)=O)=C3NC(C2)=O)C([N+]([O-])=O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.