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MtTMPK-IN-5

MtbTMPK Inhibitor

MtTMPK-IN-5 is a selective inhibitor of M. tuberculosis thymidylate kinase (MtbTMPK), exhibiting an IC50 value of 34 μM. This compound demonstrates significant antimicrobial activity against M. tuberculosis, with a minimum inhibitory concentration (MIC) of 12.5 μM. MtTMPK-IN-5 is a valuable tool for researchers investigating therapeutic strategies for tuberculosis.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2987763-18-6
Applications	MtbTMPK Inhibitor
Formula	C₂₁H₂₃N₅O₂
Molecular Weight	377.44
SMILES	CC1=CN(C(NC1=O)=O)C2CCN(CC2)CC3=CC=CC(C4=CC=CC=N4)=N3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.