N3-PEG3-C2-NHS ester is a non-cleavable linker designed for use in the synthesis of antibody-drug conjugates (ADCs), specifically facilitating the conjugation of biomolecules through versatile click chemistry approaches. This reagent features an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. Its unique characteristics make it an essential component for developing stable and effective ADCs in therapeutic research.
N3-PEG3-C2-NHS ester is a non-cleavable linker designed for use in the synthesis of antibody-drug conjugates (ADCs), specifically facilitating the conjugation of biomolecules through versatile click chemistry approaches. This reagent features an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. Its unique characteristics make it an essential component for developing stable and effective ADCs in therapeutic research.
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