N3-PEG4-C2-NHS ester is a non-cleavable 4-unit polyethylene glycol (PEG) linker designed for use in the synthesis of antibody-drug conjugates (ADCs). This compound features an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN functionalities. Due to its unique properties, N3-PEG4-C2-NHS ester is a valuable tool for the development of targeted therapeutics.
N3-PEG4-C2-NHS ester is a non-cleavable 4-unit polyethylene glycol (PEG) linker designed for use in the synthesis of antibody-drug conjugates (ADCs). This compound features an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN functionalities. Due to its unique properties, N3-PEG4-C2-NHS ester is a valuable tool for the development of targeted therapeutics.
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