N3-PEG4-C2-Pfp ester is a non-cleavable linker designed for the synthesis of antibody-drug conjugates (ADCs). This 4-unit PEG linker features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-bearing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-containing compounds, making it a versatile choice for bioconjugation applications in chemical biology and drug development.
N3-PEG4-C2-Pfp ester is a non-cleavable linker designed for the synthesis of antibody-drug conjugates (ADCs). This 4-unit PEG linker features an azide functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-bearing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-containing compounds, making it a versatile choice for bioconjugation applications in chemical biology and drug development.
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