NCB-0846
Catalog No.: A20535
TNIK inhibitor
NCB-0846 is an orally available TNIK inhibitor with an IC50 of 21?nM.
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Biological Activity
| Description | NCB-0846 is an orally available TNIK inhibitor with an IC50 of 21?nM. | |||||
|---|---|---|---|---|---|---|
| Targets |
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| Cell Research |
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Product Information
| Catalog Num | A20535 |
|---|---|
| Formula | C21H21N5O2 |
| Molecular Weight | 375.42 |
| CAS Number | 1792999-26-8 |
| SMILES | O[C@@H](CC1)CC[C@@H]1OC2=CC=CC(C=N3)=C2N=C3NC4=CC=C(N=CN5)C5=C4 |
| Synonyms | NCB 0846, NCB0846 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro | DMSO | Warmed: 70 mg/mL (186.45 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 2 mg/mL | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.64 mL | 133.18 mL | 266.37 mL |
| 0.5 mM | 5.33 mL | 26.64 mL | 53.27 mL |
| 1 mM | 2.66 mL | 13.32 mL | 26.64 mL |
| 5 mM | 0.53 mL | 2.66 mL | 5.33 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
