Neogrifolin is a selective inhibitor of KRAS, which plays a critical role in the signaling pathways associated with cancer cell proliferation and survival. This compound has demonstrated significant anti-cell viability activity against human cancer cell lines, including HeLa (IC50: 24.3 μM), SW480 (IC50: 34.6 μM), and HT29 (IC50: 30.1 μM). Neogrifolin is primarily utilized in research applications aimed at elucidating the role of KRAS in tumorigenesis and investigating potential therapeutic strategies for KRAS-driven malignancies.
Neogrifolin is a selective inhibitor of KRAS, which plays a critical role in the signaling pathways associated with cancer cell proliferation and survival. This compound has demonstrated significant anti-cell viability activity against human cancer cell lines, including HeLa (IC50: 24.3 μM), SW480 (IC50: 34.6 μM), and HT29 (IC50: 30.1 μM). Neogrifolin is primarily utilized in research applications aimed at elucidating the role of KRAS in tumorigenesis and investigating potential therapeutic strategies for KRAS-driven malignancies.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
