KRAS inhibitor-23

Catalog No.: A63636
KRAS Inhibitor
KRAS Inhibitor-23 is a selective inhibitor targeting KRAS, a critical protein involved in cell signaling pathways that regulate cell growth and differentiation. This compound demonstrates significant biological activity by effectively disrupting KRAS-mediated oncogenic signaling, making it a valuable tool in cancer research. Its application spans the investigation of KRAS mutations and their role in tumor progression, providing insights into potential therapeutic strategies for KRAS-driven malignancies.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionKRAS Inhibitor-23 is a selective inhibitor targeting KRAS, a critical protein involved in cell signaling pathways that regulate cell growth and differentiation. This compound demonstrates significant biological activity by effectively disrupting KRAS-mediated oncogenic signaling, making it a valuable tool in cancer research. Its application spans the investigation of KRAS mutations and their role in tumor progression, providing insights into potential therapeutic strategies for KRAS-driven malignancies.
Product Information
Catalog NumA63636
FormulaC32H27D3ClFN6O4
Molecular Weight620.09
CAS Number2641747-55-7
SMILESO=C1C2=C(N3[C@H](CN(CC3)C(C=C)=O)C(N2C([2H])([2H])[2H])=O)C4=CC(Cl)=C(C5=C(C=CC=C5O)F)N=C4N1C6=C(N=CC=C6C)C(C)C
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