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KRAS inhibitor-35

Catalog No.: A63692
KRAS Inhibitor
KRAS Inhibitor-35 (compound 72) is a potent inhibitor of KRAS with an IC50 of 2 nM. It effectively disrupts KRAS signaling pathways, making it a valuable tool for studying tumor biology and the role of KRAS mutations in cancer research. This compound is suitable for various in vitro and in vivo applications aimed at exploring therapeutic strategies targeting KRAS-driven malignancies.
KRAS inhibitor-35 3030078-96-4 KRAS Inhibitor
Grouped product items
Size Price Stock Qty
25mg
$2,410.00
In stock
50mg
$3,100.00
In stock
100mg
$4,160.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionKRAS Inhibitor-35 (compound 72) is a potent inhibitor of KRAS with an IC50 of 2 nM. It effectively disrupts KRAS signaling pathways, making it a valuable tool for studying tumor biology and the role of KRAS mutations in cancer research. This compound is suitable for various in vitro and in vivo applications aimed at exploring therapeutic strategies targeting KRAS-driven malignancies.
Product Information
Catalog NumA63692
FormulaC38H32F4N6O3S
Molecular Weight728.76
CAS Number3030078-96-4
SMILESC#CC1=C(C=CC2=C1C(C3=C(C4=C(C(N5CCN(CC5)C(/C(F)=C/C6=NC=CS6)=O)=NC(OC[C@]78C[C@@H](F)CN7CCC8)=N4)C=C3)F)=CC(O)=C2)F
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Cell Cycle > Ras