NH2-PEG5-OH is a PEG-based linker designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs) and antibody-drug conjugates (ADCs). This non-cleavable linker, incorporating a five-unit polyethylene glycol (PEG) structure, enhances the stability and solubility of biologically active compounds. Researchers utilize NH2-PEG5-OH to facilitate targeted degradation of proteins or deliver cytotoxic agents via ADCs, improving therapeutic efficacy in various applications.
NH2-PEG5-OH is a PEG-based linker designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs) and antibody-drug conjugates (ADCs). This non-cleavable linker, incorporating a five-unit polyethylene glycol (PEG) structure, enhances the stability and solubility of biologically active compounds. Researchers utilize NH2-PEG5-OH to facilitate targeted degradation of proteins or deliver cytotoxic agents via ADCs, improving therapeutic efficacy in various applications.
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