NICE-01

Name: NICE-01
Brand: Adooq Bioscience
SKU: A24439
Rating: 5 (288 reviews)

Catalog No.: A24439

NICE-01 (AP1867-PEG2-JQ1; AP-PEG2-JQ1) is a bifunctional compound designed to induce nuclear import of cytosolic proteins. It functions by binding proteins in distinct cellular compartments and leveraging nuclear-localized BRD4 as a “carrier” to facilitate co-import and nuclear retention of cytosolic cargoes.

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Grouped product items
Size	Price	Stock
1mg	$360.00	In stock
5mg	$1,080.00	In stock
10mg	$1,840.00	In stock
50mg	$5,520.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	NICE-01 (AP1867-PEG2-JQ1; AP-PEG2-JQ1) is a bifunctional compound designed to induce nuclear import of cytosolic proteins. It functions by binding proteins in distinct cellular compartments and leveraging nuclear-localized BRD4 as a “carrier” to facilitate co-import and nuclear retention of cytosolic cargoes.

Product Information

Catalog Num	A24439
Formula	C63H76ClN7O13S
Molecular Weight	1206.83
CAS Number	2982819-94-1
SMILES	CC(C(C(C(C=C1)=CC=C1Cl)=N[C@H]2CC(NCCOCCOCCNC(COC3=CC([C@@H](CCC(C=C4)=CC(OC)=C4OC)OC([C@H](CCCC5)N5C([C@H](C(C=C6OC)=CC(OC)=C6OC)CC)=O)=O)=CC=C3)=O)=O)=C(S7)N8C2=NN=C8C)=C7C
Synonyms	AP1867-PEG2-JQ1; AP-PEG2-JQ1
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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