Fig. 1 · Structure
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NITD-304
Anti-tuberculosis Agent
NITD-304 is an orally active anti-tuberculosis agent that targets Mycobacterium tuberculosis, including multidrug-resistant strains. It exhibits both inhibitory and bactericidal activities by disrupting mycobacterial cell wall biosynthesis. This compound demonstrates synergistic effects when combined with select antibacterial agents and has a favorable safety profile, showing minimal risk of cardiotoxicity and drug-drug interactions. NITD-304 is suitable for research focused on tuberculosis and multidrug-resistant tuberculosis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1473450-60-0 |
| Applications | Anti-tuberculosis Agent |
| Formula | C17H20Cl2N2O |
| Molecular Weight | 339.26 |
| SMILES | O=C(NC1CCC(C)(CC1)C)C2=CC3=C(C=C(C=C3Cl)Cl)N2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.