Nitro-PDS-Tubulysin M

Catalog No.: A18514

Nitro-PDS-Tubulysin M

Nitro-PDS-Tubulysin M Chemical Structure

CAS NO. 1941168-69-9

Nitro-PDS-Tubulysin M is a drug-linker conjugate for ADC with potent antitumor activity by using Tubulysin M (a tubulin polymerization inhibitor), linked via the ADC linker Nitro-PDS.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

Nitro-PDS-Tubulysin M is a drug-linker conjugate for ADC with potent antitumor activity by using Tubulysin M (a tubulin polymerization inhibitor), linked via the ADC linker Nitro-PDS.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 9.04 mL 45.19 mL 90.38 mL
0.5 mM 1.81 mL 9.04 mL 18.08 mL
1 mM 0.9 mL 4.52 mL 9.04 mL
5 mM 0.18 mL 0.9 mL 1.81 mL

*The above data is based on the productmolecular weight 1106.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18514
CAS No. 1941168-69-9
Formula C54H73N8O11S3
M. Wt 1106.4
Purity >98%
SMILES O=C(O)[[email protected]@H](C)C[[email protected]@H](NC(C1=CSC([[email protected]](OC(C)=O)C[[email protected]@H](N(C)C([[email protected]@H](NC([[email protected]@H]2[N+](CC3=CC=C(NC(OC[[email protected]](SSC4=CC=C([N+]([O-])=O)N=C4)C)=O)C=C3)(C)CCCC2)=O)[[email protected]@H](C)CC)=O)C(C)C)=N1)=O)CC5=CC=CC=C5
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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