Fig. 1 · Structure
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Nitroxoline
Antibiofilm Agent
Nitroxoline, an antibiotic and orally active antibiofilm agent, primarily targets the reduction and dispersal of biofilms formed by Pseudomonas aeruginosa. Its mechanism involves the chelation of iron and zinc, which disrupts biofilm integrity. Nitroxoline is applicable in the study of urinary tract infections and possesses potential research implications in cancer biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 4008-48-4 |
| Applications | Antibiofilm Agent |
| Formula | C9H6N2O3 |
| Molecular Weight | 190.16 |
| Synonyms | 8-Hydroxy-5-nitroquinoline; 5-Nitro-8-quinolinol |
| SMILES | OC1=C2N=CC=CC2=C([N+]([O-])=O)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.