Nomifensine-d3 maleate is a deuterium-labeled derivative of Nomifensine maleate, a potent inhibitor of norepinephrine (NE) and dopamine (DA) reuptake. It effectively blocks the reuptake of NE, DA, and serotonin (5-HT) in rat brain synaptosomes, with IC50 values of 6.6 nM, 48 nM, and 830 nM, respectively. This compound displays antidepressant and analgesic properties, and is applicable in research related to neurodegenerative diseases, substance addiction, and pain mechanisms.
Nomifensine-d3 maleate is a deuterium-labeled derivative of Nomifensine maleate, a potent inhibitor of norepinephrine (NE) and dopamine (DA) reuptake. It effectively blocks the reuptake of NE, DA, and serotonin (5-HT) in rat brain synaptosomes, with IC50 values of 6.6 nM, 48 nM, and 830 nM, respectively. This compound displays antidepressant and analgesic properties, and is applicable in research related to neurodegenerative diseases, substance addiction, and pain mechanisms.
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