Norjuziphine

Catalog No.: A97463
Alkaloid
Norjuziphine is an alkaloid derived from the lotus flower (Nelumbo nucifera) that primarily targets melanogenesis. It effectively inhibits melanin production in murine B16 melanoma 4A5 cells induced by theophylline, demonstrating an IC50 value of 14.4 μM. This compound is valuable for research into skin whitening and the treatment of related skin pigmentation disorders.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNorjuziphine is an alkaloid derived from the lotus flower (Nelumbo nucifera) that primarily targets melanogenesis. It effectively inhibits melanin production in murine B16 melanoma 4A5 cells induced by theophylline, demonstrating an IC50 value of 14.4 μM. This compound is valuable for research into skin whitening and the treatment of related skin pigmentation disorders.
Product Information
Catalog NumA97463
FormulaC17H19NO3
Molecular Weight285.34
CAS Number74119-87-2
SMILESCOC1=CC=C(CCN2)C([C@H]2CC3=CC=C(C=C3)O)=C1O
Synonyms(-)-Norjuziphine
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