NP-BTA is an allosteric inhibitor of glutaminyl-tRNA synthetase (GlnRS), demonstrating significant antifungal activity. It exhibits an MIC50 of 6.25 μM against Candida albicans, making it a valuable tool for research applications focused on fungal infections. Its mechanism contributes to the understanding of tRNA synthetase inhibition in the context of antifungal drug development.
NP-BTA is an allosteric inhibitor of glutaminyl-tRNA synthetase (GlnRS), demonstrating significant antifungal activity. It exhibits an MIC50 of 6.25 μM against Candida albicans, making it a valuable tool for research applications focused on fungal infections. Its mechanism contributes to the understanding of tRNA synthetase inhibition in the context of antifungal drug development.
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