NS2B/NS3-IN-4 is an allosteric inhibitor targeting the NS2B/NS3 protease of dengue virus serotype 2 (DENV2) and Zika virus (ZIKV). It demonstrates IC50 values of 0.69 µM for DENV2 and 1.04 µM for ZIKV proteases, highlighting its potent enzymatic inhibition. This compound serves as a valuable tool in antiviral research, particularly for elucidating mechanisms of viral replication and developing therapeutic strategies against flavivirus infections.
NS2B/NS3-IN-4 is an allosteric inhibitor targeting the NS2B/NS3 protease of dengue virus serotype 2 (DENV2) and Zika virus (ZIKV). It demonstrates IC50 values of 0.69 µM for DENV2 and 1.04 µM for ZIKV proteases, highlighting its potent enzymatic inhibition. This compound serves as a valuable tool in antiviral research, particularly for elucidating mechanisms of viral replication and developing therapeutic strategies against flavivirus infections.
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