NS2B/NS3-IN-5 is an allosteric inhibitor targeting the NS2B/NS3 protease of Dengue Virus Serotype 2 (DENV2) and Zika Virus (ZIKV). It demonstrates effective inhibitory activity with IC50 values of 0.67 µM against ZIKV and 4.38 µM against DENV2 NS2B/NS3 proteases. This compound presents significant potential for research applications in virology, specifically in the development of antiviral therapies targeting these flavivirus proteases.
NS2B/NS3-IN-5 is an allosteric inhibitor targeting the NS2B/NS3 protease of Dengue Virus Serotype 2 (DENV2) and Zika Virus (ZIKV). It demonstrates effective inhibitory activity with IC50 values of 0.67 µM against ZIKV and 4.38 µM against DENV2 NS2B/NS3 proteases. This compound presents significant potential for research applications in virology, specifically in the development of antiviral therapies targeting these flavivirus proteases.
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