NS2B/NS3-IN-6

Catalog No.: A53603
NS2B/NS3 Inhibitor
NS2B/NS3-IN-6 is an allosteric inhibitor targeting the NS2B/NS3 protease of Dengue virus (DENV) and Zika virus (ZIKV). It exhibits IC50 values of 2.23 µM and 25.2 µM against ZIKV and DENV proteases, respectively. This compound is valuable for research applications focused on developing antiviral therapies and understanding the enzymatic mechanisms of flavivirus proteases.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNS2B/NS3-IN-6 is an allosteric inhibitor targeting the NS2B/NS3 protease of Dengue virus (DENV) and Zika virus (ZIKV). It exhibits IC50 values of 2.23 µM and 25.2 µM against ZIKV and DENV proteases, respectively. This compound is valuable for research applications focused on developing antiviral therapies and understanding the enzymatic mechanisms of flavivirus proteases.
Product Information
Catalog NumA53603
FormulaC19H19N3O5S2
Molecular Weight433.50
CAS Number2459657-57-7
SMILESO=S(N1[C@@H](CCC1)C(NC2=NC3=CC(O)=C(O)C=C3S2)=O)(C4=CC=C(C=C4)C)=O
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