NSC 288387 is a pan-flavivirus methyltransferase (MTase) inhibitor that targets the S-adenosylmethionine (SAM) binding pocket. It demonstrates significant antiviral activity, inhibiting Zika virus (ZIKV) replication with an IC50 of 0.2 μM. This compound is useful in research applications focused on flavivirus infections and the mechanisms of viral replication.
NSC 288387 is a pan-flavivirus methyltransferase (MTase) inhibitor that targets the S-adenosylmethionine (SAM) binding pocket. It demonstrates significant antiviral activity, inhibiting Zika virus (ZIKV) replication with an IC50 of 0.2 μM. This compound is useful in research applications focused on flavivirus infections and the mechanisms of viral replication.
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