Fig. 1 · Structure
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o-Phenanthroline monohydrate
MMP Inhibitor
o-Phenanthroline monohydrate is a potent MMP inhibitor that acts by chelating divalent metal ions, particularly iron (Fe2+), forming a stable red complex that absorbs light maximally at 510 nm. This compound has demonstrated the ability to prevent chromosomal aberrations in cells exposed to streptozotocin, thereby highlighting its significance in cellular and molecular biology research. It is widely utilized in studies investigating metalloproteinases and their role in various biological processes and disease states.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 5144-89-8 |
| Applications | MMP Inhibitor |
| Formula | C12H10N2O |
| Molecular Weight | 198.22 |
| Synonyms | 1,10-Phenanthroline monohydrate |
| SMILES | C12=C(N=CC=C3)C3=CC=C1C=CC=N2.O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.