Fig. 1 · Structure
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o-Phenanthroline
MMP Inhibitor
o-Phenanthroline is a potent matrix metalloproteinase (MMP) inhibitor that also acts as a metal chelator. It effectively prevents chromosomal aberrations in cells treated with streptozotocin. Within biological systems, o-Phenanthroline forms a stable red chelate with Fe2+, exhibiting peak absorbance at 510 nm. This compound is widely utilized in research applications focusing on metalloprotein interactions and cellular responses to stress.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 66-71-7 |
| Applications | MMP Inhibitor |
| Formula | C12H8N2 |
| Molecular Weight | 180.21 |
| Synonyms | 1,10-Phenanthroline |
| SMILES | C12=C(N=CC=C3)C3=CC=C1C=CC=N2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.