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OH-Glu-Val-Cit-PAB-MMAE

Catalog No.: A41432
ADC Linker
OH-Glu-Val-Cit-PAB-MMAE is a cleavable antibody-drug conjugate (ADC) linker that incorporates a potent tubulin inhibitor, MMAE. This compound is designed for the synthesis of ADCs, facilitating targeted delivery of cytotoxic agents to cancer cells. Its unique structure allows for selective release of MMAE, enhancing therapeutic efficacy while minimizing off-target effects. This reagent is valuable for researchers developing novel ADCs in the field of cancer treatment.
OH-Glu-Val-Cit-PAB-MMAE 1895916-23-0 ADC Linker
Grouped product items
Size Price Stock Qty
5mg
$330.00
In stock
10mg
$530.00
In stock
25mg
$1,050.00
In stock
50mg
$1,705.00
In stock
100mg
$2,665.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionOH-Glu-Val-Cit-PAB-MMAE is a cleavable antibody-drug conjugate (ADC) linker that incorporates a potent tubulin inhibitor, MMAE. This compound is designed for the synthesis of ADCs, facilitating targeted delivery of cytotoxic agents to cancer cells. Its unique structure allows for selective release of MMAE, enhancing therapeutic efficacy while minimizing off-target effects. This reagent is valuable for researchers developing novel ADCs in the field of cancer treatment.
Product Information
Catalog NumA41432
FormulaC63H100N10O15
Molecular Weight1237.53
CAS Number1895916-23-0
SMILESO[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCC(O)=O)=O)=O)=O)=O)=O)=O)=O)OC)=O
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Antibody-drug Conjugates (ADC) > ADC Linker