Olcorolimus

Catalog No.: A36114
Anti-inflammatory Agent
Olcorolimus is a derivative of Rapamycin that functions as an anti-inflammatory agent. It effectively reduces levels of IL-4 and IL-5, as well as the presence of eosinophils, neutrophils, and lymphocytes, while also inhibiting cellular fibronectin, lung epithelial cell proliferation, and mucus hypersecretion in Ovalbumin-sensitized BALB/c mice. This compound is valuable for research in the fields of inflammation and immunology, particularly for models related to asthma.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionOlcorolimus is a derivative of Rapamycin that functions as an anti-inflammatory agent. It effectively reduces levels of IL-4 and IL-5, as well as the presence of eosinophils, neutrophils, and lymphocytes, while also inhibiting cellular fibronectin, lung epithelial cell proliferation, and mucus hypersecretion in Ovalbumin-sensitized BALB/c mice. This compound is valuable for research in the fields of inflammation and immunology, particularly for models related to asthma.
Product Information
Catalog NumA36114
FormulaC51H81NO12
Molecular Weight900.19
CAS Number186752-78-3
SMILESO=C1N2[C@](CCCC2)([H])C(O[C@](CC[C@@H](/C=C([C@H]([C@H](C([C@H](C)C[C@H](C)/C=C/C=C/C=C(C)/[C@@H](OC)C[C@@]3([H])O[C@](O)([C@@H](CC3)C)C1=O)=O)OC)O)\C)C)([H])[C@H](C)C[C@H]4C[C@H]([C@H](O)CC4)OC)=O
SynonymsSAR-943
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