Fig. 1 · Structure
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Olgotrelvir sodium
Mpro Inhibitor
Olgotrelvir sodium is a potent inhibitor of the coronavirus main protease (Mpro) and human cathepsin L, functioning as an orally active dual inhibitor. It is metabolized into its active form, AC1115, within whole blood or plasma. This reagent demonstrates significant efficacy in inhibiting SARS-CoV-2 replication and cellular entry, making it a valuable tool for research into coronavirus biology and therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2763596-72-9 |
| Applications | Mpro Inhibitor |
| Formula | C22H29N4NaO7S |
| Molecular Weight | 516.54 |
| Synonyms | STI-1558 sodium |
| SMILES | O=C(NCC1)[C@@H]1C[C@@H](C(O)S(=O)(O[Na])=O)NC([C@H](CC(C)C)NC(C2=CC3=CC=CC=C3N2)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.