Fig. 1 · Structure

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Olgotrelvir

Mpro Inhibitor

Olgotrelvir is a potent inhibitor of the coronavirus main protease (Mpro) and human cathepsin L. Its oral bioavailability allows for effective inhibition of SARS-CoV-2 replication and entry into host cells. By being converted to its active form, AC1115, in biological fluids, Olgotrelvir serves as a valuable research tool in the study of coronavirus-related pathologies and therapeutic interventions.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2763596-71-8
Applications Mpro Inhibitor
Formula C22H30N4O7S
Molecular Weight 494.56
Synonyms STI-1558
SMILES
O=C(NCC1)[C@@H]1C[C@@H](C(O)S(=O)(O)=O)NC([C@H](CC(C)C)NC(C2=CC3=CC=CC=C3N2)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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