Orellanine is a potent fungal nephrotoxin primarily known for its mechanism as a competitive inhibitor of alkaline phosphatase. This compound effectively induces apoptosis in proximal tubular cells and clear cell renal cell carcinoma (ccRCC) cell lines. Orellanine serves as a valuable tool for research focused on nephrotoxicity and the pathophysiology of ccRCC.
Orellanine is a potent fungal nephrotoxin primarily known for its mechanism as a competitive inhibitor of alkaline phosphatase. This compound effectively induces apoptosis in proximal tubular cells and clear cell renal cell carcinoma (ccRCC) cell lines. Orellanine serves as a valuable tool for research focused on nephrotoxicity and the pathophysiology of ccRCC.
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