Fig. 1 · Structure
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Otaplimastat hydrochloride
MMP Inhibitor
Otaplimastat hydrochloride is a selective inhibitor of matrix metalloproteinases (MMPs), known to mitigate N-methyl-D-aspartate (NMDA) receptor-mediated excitotoxicity through competitive binding. This compound also demonstrates antioxidant properties, making it relevant for studies involving oxidative stress. Otaplimastat hydrochloride is primarily utilized in research related to brain ischemic injury and neuronal protection.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1176758-02-3 |
| Applications | MMP Inhibitor |
| Formula | C28H35ClN6O5 |
| Molecular Weight | 571.07 |
| Synonyms | SP-8203 hydrochloride |
| SMILES | CC(N(CCCN1C(NC2=C(C=CC=C2)C1=O)=O)CCCCNCCCN3C(NC4=C(C=CC=C4)C3=O)=O)=O.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.