Fig. 1 · Structure
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Otaplimastat
MMP Inhibitor
Otaplimastat is a matrix metalloproteinase (MMP) inhibitor that effectively suppresses N-methyl-D-aspartate (NMDA) receptor-mediated excitotoxicity through competitive inhibition. In addition to its role as an MMP inhibitor, Otaplimastat displays antioxidant properties. This compound is valuable for research focused on brain ischemic injury and related neuroprotective mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1176758-04-5 |
| Applications | MMP Inhibitor |
| Formula | C28H34N6O5 |
| Molecular Weight | 534.61 |
| Synonyms | SP-8203 |
| SMILES | CC(N(CCCN1C(NC2=C(C=CC=C2)C1=O)=O)CCCCNCCCN3C(NC4=C(C=CC=C4)C3=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.