Drug Intermediate

Cat. No.

A65602

CAS No.

2591300-32-0

STING agonist-33

STING agonist-33 is a potent agonist of STING (stimulator of interferon genes) derived from 4-ethyl-2-methylthiazole-5-carboxylic acid. It acts by activating the STING pathway, which plays a crucial role in the innate immune response by promoting the production of type I interferons. This reagent is valuable for research applications focused on immune modulation, cancer therapy, and infectious diseases, as it can enhance the body's antiviral and antitumor defenses.

Cat. No.

A91693

CAS No.

9001-91-6

Murine Plasminogen

Murine Plasminogen is the inactive precursor of the serine protease plasmin, sourced from freshly collected murine plasma. This protein plays a critical role in fibrinolysis, where it is converted into plasmin by activators such as urokinase, streptokinase, or tissue plasminogen activator. It is utilized in research applications involving coagulation, thrombolysis, and extracellular matrix modulation, making it essential for studies on wound healing and related physiological processes.

Cat. No.

A97856

CAS No.

637-88-7

1,4-Cyclohexanedione

1,4-Cyclohexanedione serves as a crucial drug intermediate due to its role as a substrate for the EryKR1 domain. This compound exhibits unique biocatalytic activity and stereospecificity, making it valuable for various synthetic applications in pharmaceutical research. Its ability to participate in stereochemical transformations further supports its utility in the development of complex organic molecules.

Cat. No.

A98382

CAS No.

498-62-4

3-Thiophenecarboxaldehyde

Synonyms: 3-TC

3-Thiophenecarboxaldehyde is a thiophene derivative that serves as a substrate for biocatalytic reduction to 3-thiophenemethanol, facilitated by Pseudomonas putida S12 cells. This compound functions as an important intermediate in synthetic pathways. However, it exhibits toxicity toward Pseudomonas putida S12 at elevated concentrations, negatively impacting specific growth rates and final biomass yields. Its unique properties make it useful for research in biocatalysis and metabolic engineering.

Cat. No.

A99692

CAS No.

5588-21-6

Cintriamide

Synonyms: Cintramide

Cintriamide is a crucial synthesis intermediate used in the preparation of photoswitchable epothilone-based microtubule stabilizers. Its unique chemical properties facilitate the development of novel compounds targeting microtubule dynamics, making it vital for advancing research in cancer therapeutics and related fields. This compound serves as a valuable building block for scientists exploring new therapeutic avenues in antineoplastic drug development.

Cat. No.

B10424

CAS No.

863238-52-2

Sal-AMP

Sal-AMP is an acyl-adenylate intermediate that serves as a substrate for MbtA, facilitating the loading onto the thiolation domain of MbtB. This compound plays a critical role in the biosynthetic pathway of mycobacterial compounds and is valuable for research investigating tuberculosis and related bacterial processes. Its use can aid in understanding the mechanisms of mycobacterial metabolism and potential drug targets.