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Impurities & Reference Standards

Impurities & Reference Standards collects environmental contaminants, industrial chemicals and drug stereoisomers. Many entries are substances monitored in environmental and food analysis, such as the plasticizer dimethyl phthalate and the polycyclic aromatic hydrocarbon fluorene. Flame retardants are represented by the organophosphate triphenyl phosphate and by brominated compounds. Perfluorodecanoic acid belongs to the per- and polyfluoroalkyl substances (PFAS), a class known for persistence in the environment. A second group holds enantiomers and isomers of research compounds, such as (R)-Asundexian, the (R)-enantiomer of the factor XIa inhibitor asundexian. Such isomers support stereochemical comparison and the development of chromatographic separation methods. Process-related and degradation compounds of individual drugs are listed separately under Drug Impurity.

3 Items

  • Dibenzo(a,i)pyrene
    Cat. No.
    A53801
    CAS No.
    189-55-9

    Dibenzo(a,i)pyrene

    Dibenzo(a,i)pyrene is a polycyclic aromatic hydrocarbon that serves as a carcinogenic ligand for the TCDD (Ah) receptor. It has been shown to induce DNA adduct formation while upregulating p53 and p21WAF1 protein levels in diploid lung fibroblasts. Additionally, Dibenzo(a,i)pyrene alters cell cycle dynamics, increasing the S phase population and leading to G0/G1 and G2/M phase decreases, resulting in S phase delay or arrest. This compound is relevant for applications in cancer research.

    In stock View Details
    1 mg
    $90.00
    5 mg
    $285.00
    All 5 sizes
  • (Rac)-Methylindazone
    Cat. No.
    A66546
    CAS No.
    53108-00-2

    (Rac)-Methylindazone

    Synonyms: (Rac)-IAA-94

    (Rac)-Methylindazone is the racemic mixture of Methylindazone, a potent blocker of the CLIC1 ion channel. This compound exhibits significant biological activity in modulating chloride ion transport, making it a valuable tool in research focused on ion channel function and related physiological processes. Potential applications include studies in cellular signaling and the investigation of CLIC1's role in various pathophysiological conditions.

    In stock View Details
    25 mg
    $1,405.00
    50 mg
    $1,790.00
    All 3 sizes
  • Chrysene
    Cat. No.
    A92742
    CAS No.
    218-01-9

    Chrysene

    Chrysene is a high molecular weight polycyclic aromatic hydrocarbon (PAH) recognized for its role as a carcinogenic inducer. This compound exhibits significant potential for inducing malignancies in various biological systems, making it a valuable tool for cancer research. Chrysene is commonly used in studies aimed at elucidating the mechanisms of carcinogenesis and understanding the effects of environmental pollutants on human health.

    In stock View Details
    500 mg
    $30.00
    All 1 sizes

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