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Impurities & Reference Standards

Impurities & Reference Standards collects environmental contaminants, industrial chemicals and drug stereoisomers. Many entries are substances monitored in environmental and food analysis, such as the plasticizer dimethyl phthalate and the polycyclic aromatic hydrocarbon fluorene. Flame retardants are represented by the organophosphate triphenyl phosphate and by brominated compounds. Perfluorodecanoic acid belongs to the per- and polyfluoroalkyl substances (PFAS), a class known for persistence in the environment. A second group holds enantiomers and isomers of research compounds, such as (R)-Asundexian, the (R)-enantiomer of the factor XIa inhibitor asundexian. Such isomers support stereochemical comparison and the development of chromatographic separation methods. Process-related and degradation compounds of individual drugs are listed separately under Drug Impurity.

4 Items

  • (6R)-FR054
    Cat. No.
    A31200
    CAS No.
    10378-06-0

    (6R)-FR054

    (6R)-FR054 is a less active isomer of FR054, acting primarily as a modulator of biological pathways influenced by the parent compound. This reagent provides a valuable tool for comparative studies aimed at elucidating the mechanisms of action and specific contributions of the more active isomer. Researchers can utilize (6R)-FR054 in the development of experimental designs that require an understanding of molecular interactions and signaling processes.

    In stock View Details
    5 mg
    $25.00
    10 mg
    $35.00
    All 5 sizes
  • WAY-120744
    Cat. No.
    A40166
    CAS No.
    127810-07-5

    WAY-120744

    WAY-120744 is a novel naphthalenyl 3H-1,2,3,5-oxathiadiazole 2-oxide that acts as a potent modulator of biological targets relevant to chemotherapeutic strategies. This compound demonstrates significant anti-cancer activity, making it suitable for applications in cancer research and drug development. Its unique structure permits exploration of mechanisms of action in various cellular contexts, providing valuable insights into the modulation of signaling pathways.

    In stock View Details
    25 mg
    $1,275.00
    All 1 sizes
  • Dibenzo(a,i)pyrene
    Cat. No.
    A53801
    CAS No.
    189-55-9

    Dibenzo(a,i)pyrene

    Dibenzo(a,i)pyrene is a polycyclic aromatic hydrocarbon that serves as a carcinogenic ligand for the TCDD (Ah) receptor. It has been shown to induce DNA adduct formation while upregulating p53 and p21WAF1 protein levels in diploid lung fibroblasts. Additionally, Dibenzo(a,i)pyrene alters cell cycle dynamics, increasing the S phase population and leading to G0/G1 and G2/M phase decreases, resulting in S phase delay or arrest. This compound is relevant for applications in cancer research.

    In stock View Details
    1 mg
    $90.00
    5 mg
    $285.00
    All 5 sizes
  • 11alpha-Hydroxyprogesterone
    Cat. No.
    B21627
    CAS No.
    80-75-1

    11alpha-Hydroxyprogesterone

    11alpha-Hydroxyprogesterone is an isomer of 11beta-Hydroxyprogesterone, serving as a valuable experimental control in research. It exhibits biological activity as a modulator of steroid receptors and can be utilized to investigate the effects of glucocorticoids and mineralocorticoids in cellular systems. Its application includes studying the activation of human mineralocorticoid receptors and the inhibition of 11β-Hydroxysteroid dehydrogenase, facilitating a deeper understanding of steroid hormone signaling pathways.

    In stock View Details
    25 mg
    $40.00
    50 mg
    $65.00
    All 2 sizes

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