OTS514 hydrochloride

Catalog No.: A31520
Apoptosis Inducer
OTS514 hydrochloride is a potent inhibitor of the TOPK kinase, exhibiting an IC50 value of 2.6 nM. This compound effectively suppresses the proliferation of TOPK-positive cancer cells by inducing cell cycle arrest and apoptosis. OTS514 hydrochloride is a valuable tool for research focusing on cancer biology and potential therapeutic strategies targeting apoptotic pathways.
Grouped product items
Size Price Stock Qty
1mg
$45.00
In stock
2mg
$80.00
In stock
5mg
$145.00
In stock
10mg
$270.00
In stock
25mg
$490.00
In stock
50mg
$645.00
In stock
100mg
$800.00
In stock
500mg
$1,550.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionOTS514 hydrochloride is a potent inhibitor of the TOPK kinase, exhibiting an IC50 value of 2.6 nM. This compound effectively suppresses the proliferation of TOPK-positive cancer cells by inducing cell cycle arrest and apoptosis. OTS514 hydrochloride is a valuable tool for research focusing on cancer biology and potential therapeutic strategies targeting apoptotic pathways.
Product Information
Catalog NumA31520
FormulaC21H21ClN2O2S
Molecular Weight400.92
CAS Number2319647-76-0
SMILESO=C1NC2=C(C(C3=CC=C([C@@H](C)CN)C=C3)=C(O)C=C2C)C4=C1SC=C4.[H]Cl
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