Oxypeucedanin is a furanocoumarin derivative that acts as a potent blocker of the hKv1.5 current, with an IC50 of 76 nM. This compound demonstrates significant biological activities, including the induction of cell cycle arrest and apoptosis, as well as acting as a PI3K/AKT/NF-κB, MAPK, and ROS inhibitor. Its diverse applications include anticancer research, anti-inflammatory studies, antioxidant assays, and investigations into antiarrhythmic effects, making it a valuable reagent for various areas of biochemical research.
Oxypeucedanin is a furanocoumarin derivative that acts as a potent blocker of the hKv1.5 current, with an IC50 of 76 nM. This compound demonstrates significant biological activities, including the induction of cell cycle arrest and apoptosis, as well as acting as a PI3K/AKT/NF-κB, MAPK, and ROS inhibitor. Its diverse applications include anticancer research, anti-inflammatory studies, antioxidant assays, and investigations into antiarrhythmic effects, making it a valuable reagent for various areas of biochemical research.
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