Fig. 1 · Structure
Documents & Downloads
PAT-347
ATX Inhibitor
PAT-347 is an inhibitor of Autotaxin (ATX), a secreted enzyme that catalyzes the hydrolysis of lysophosphatidylcholine (LPC) to produce lysophosphatidic acid (LPA). By modulating LPA levels, PAT-347 enables the investigation of ATX's role in various biological processes, including cell proliferation, migration, and differentiation. This compound is useful in research related to cancer, inflammation, and other pathophysiological conditions where ATX and LPA signaling are implicated.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1689554-51-5 |
| Applications | ATX Inhibitor |
| Formula | C28H21ClF2N2O3S |
| Molecular Weight | 538.99 |
| SMILES | O=C(O)C1=CC=CC(SC2=C(C)N(CC(N3CC4(C5=C3C=CC=C5)CC4)=O)C6=C2C=CC(Cl)=C6F)=C1F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.