Fig. 1 · Structure
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Pazufloxacin mesylate
Antimicrobial Agent
Pazufloxacin mesylate is an orally active fluoroquinolone antimicrobial targeting DNA gyrase. It demonstrates significant antimicrobial activity with IC50 values of 0.88 μg/mL against E. coli and 1.9 μg/mL against P. aeruginosa. The compound exhibits a broad spectrum of effectiveness, with MIC90 values ranging from 0.025 to 100 μg/mL against various Gram-positive and Gram-negative bacteria, non-fermenters, Legionella spp., and anaerobes. Pazufloxacin mesylate is suitable for research into systemic infections, lung infections, urinary tract infections, and Legionella pneumonia.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 163680-77-1 |
| Applications | Antimicrobial Agent |
| Formula | C17H19FN2O7S |
| Molecular Weight | 414.41 |
| Synonyms | T-3762; Pazufloxacin methanesulfonate; Pazufloxacin mesilate |
| SMILES | O=C(C(C1=O)=CN2[C@@H](C)COC3=C(C4(N)CC4)C(F)=CC1=C23)O.CS(=O)(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.