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Pazufloxacin

Antimicrobial Agent

Pazufloxacin is an orally active fluoroquinolone antimicrobial agent that primarily targets DNA gyrase. It demonstrates potent antibacterial activity with IC50 values of 0.88 μg/mL against Escherichia coli and 1.9 μg/mL against Pseudomonas aeruginosa. Pazufloxacin exhibits broad-spectrum efficacy, with MIC90 values ranging from 0.025 to 100 μg/mL across various Gram-positive and Gram-negative bacteria, non-fermenting bacteria, Legionella species, and anaerobes. This compound is suitable for research focusing on systemic infections, pulmonary infections, urinary tract infections, and Legionella pneumonia.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	127045-41-4
Applications	Antimicrobial Agent
Formula	C₁₆H₁₅FN₂O₄
Molecular Weight	318.30
Synonyms	T3761
SMILES	O=C(C(C1=O)=CN2[C@@H](C)COC3=C(C4(N)CC4)C(F)=CC1=C23)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.