Fig. 1 · Structure

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PDF-IN-2

PDF Inhibitor

PDF-IN-2 is a potent inhibitor of peptidyl deformylase (PDF), exhibiting average IC50 values of 0.25, 0.50, and 0.34 nM against Streptococcus pneumoniae PDF wild-type and mutant strains (G70V and G70D). Additionally, it demonstrates average MIC values of 0.16, 0.33, and 0.25 μg/mL for the same bacterial strains. This compound is valuable for research applications targeting infectious diseases and exploring potential therapeutic interventions.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 949197-97-1
Applications PDF Inhibitor
Formula C19H26FN5O4
Molecular Weight 407.44
SMILES
F[C@H]1CN(C([C@H](CC2CCCC2)CN(C=O)O)=O)[C@H](C(NC3=NC=CN=C3)=O)C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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