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pep-10L peptide

Catalog No.: A64831
GPVI Antagonist
Pep-10L peptide is a glycoprotein VI (GPVI) antagonist that exhibits inhibition with Ki values of 180, 225, and 179 μM for CPR, GPO-1, and Type 1 collagen, respectively. This peptide demonstrates significant anti-thrombotic effects, making it valuable for research in platelet function and thrombus formation. Pep-10L is useful in studies aimed at exploring GPVI signaling pathways and developing therapies for thrombotic diseases.
pep-10L peptide 1159846-95-3 GPVI Antagonist
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPep-10L peptide is a glycoprotein VI (GPVI) antagonist that exhibits inhibition with Ki values of 180, 225, and 179 μM for CPR, GPO-1, and Type 1 collagen, respectively. This peptide demonstrates significant anti-thrombotic effects, making it valuable for research in platelet function and thrombus formation. Pep-10L is useful in studies aimed at exploring GPVI signaling pathways and developing therapies for thrombotic diseases.
Product Information
Catalog NumA64831
FormulaC69H89N13O24
Molecular Weight1484.52
CAS Number1159846-95-3
SequenceTyr-Ser-Asp-Thr-Asp-Trp-Leu-Tyr-Phe-Ser-Thr-Ser
Sequence shorteningYSDTDWLYFSTS
SMILESC([C@@H](C(N[C@H](C(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CO)=O)[C@@H](C)O)=O)CO)=O)=O)=O)CC(C)C)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC3=CC=C(O)C=C3)N)=O)CO)=O)CC(O)=O)=O)[C@@H](C)O)=O)CC(O)=O)=O)C=4C=5C(NC4)=CC=CC5
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