PF-00446687

Catalog No.: A21382

MC4R agonist

PF-00446687

PF-00446687 Chemical Structure

CAS NO. 862281-92-3

PF-00446687 is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12????1 nM. Pf-446687 is brain penetrant.

Availability: In stock

Package Price Qty
5 mg
$315.00
10 mg
$543.00
50 mg
$1,610.00
100 mg
$3,220.00
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Biological Activity

PF-00446687 is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12????1 nM. Pf-446687 is brain penetrant.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.25 mL 106.25 mL 212.5 mL
0.5 mM 4.25 mL 21.25 mL 42.5 mL
1 mM 2.12 mL 10.62 mL 21.25 mL
5 mM 0.42 mL 2.12 mL 4.25 mL

*The above data is based on the productmolecular weight 470.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21382
Actions Agonist
M. Wt 470.59
Formula C28H36F2N2O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 862281-92-3
Synonyms PF00446687, PF 00446687
SMILES O=C([[email protected]]1[[email protected]](C2=C(C=C(F)C=C2)F)CN(C(C)(C)C)C1)N3C[[email protected]]([[email protected]](O)(C4=CC=CC=C4)[[email protected]@H](C)C3)C

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