|Discription||PF-06409577 is orally bioavailable AMPK activator with EC50 of 7 nM for α1β1γ1 in the TR-FRET assay and it shows no detectable inhibition of hERG in a patch-clamp assay (100 μM) and was not an inhibitor (IC50 > 100 μM) of the microsomal activities of major human cytochrome P450 isoforms.|
|Synonyms||PF06409577, PF 06409577|
Store lyophilized at -20ºC, keep desiccated.
|In vitro||DMSO||63 mg/mL (184.32 mM)|
|Ethanol||63 mg/mL (184.32 mM)|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||29.26 mL||146.29 mL||292.58 mL|
|0.5 mM||5.85 mL||29.26 mL||58.52 mL|
|1 mM||2.93 mL||14.63 mL||29.26 mL|
|5 mM||0.59 mL||2.93 mL||5.85 mL|
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2