Customer Appreciation Sale.
15% off with promo code "APPRECIATION2023" on check out or purchase order

PF-06447475

Catalog No.: A15504

LRRK2 inhibitor

PF-06447475

PF-06447475 Chemical Structure

CAS NO. 1527473-33-1

PF-06447475 is a highly potent, selective, brain penetrant LRRK2 inhibitor with IC50 of 3 nM/11 nM for Wt LRRK2/G2019S LRRK2 respectively.

Availability: In stock

Package Price Qty
10 mg
$65.00
25 mg
$90.00
50 mg
$135.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

PF-06447475 is a highly potent, selective, brain penetrant LRRK2 inhibitor with IC50 of 3 nM/11 nM for Wt LRRK2/G2019S LRRK2 respectively.
Targets
LRRK2 G2019S LRRK2
3nM11nM
In vitro DMSO 56 mg/mL (183.4 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.75 mL 163.76 mL 327.51 mL
0.5 mM 6.55 mL 32.75 mL 65.5 mL
1 mM 3.28 mL 16.38 mL 32.75 mL
5 mM 0.66 mL 3.28 mL 6.55 mL

*The above data is based on the productmolecular weight 305.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15504
Actions Inhibitor
CAS No. 1527473-33-1
Formula C17H15N5O
M. Wt 305.33
Purity >98%
Synonyms PF06447475, PF 06447475
SMILES C1COCCN1C2=NC=NC3=C2C(=CN3)C4=CC=CC(=C4)C#N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy PF-06447475 | PF-06447475 Supplier | purchase | cost | manufacturer | order | distributor | buy 1527473-33-1| 1527473-33-1 Supplier | purchase 1527473-33-1 | 1527473-33-1 cost | 1527473-33-1 manufacturer | order 1527473-33-1 | 1527473-33-1 distributor
Rewards