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Publications citing Adooq Products
Chemical Information
| Catalog Num | A15504 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 305.33 |
| Formula | C17H15N5O |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1527473-33-1 |
| Synonyms | PF06447475, PF 06447475 |
| SMILES | C1COCCN1C2=NC=NC3=C2C(=CN3)C4=CC=CC(=C4)C#N |
Description |
PF-06447475 is a highly potent, selective, brain penetrant LRRK2 inhibitor with IC50 of 3 nM/11 nM for Wt LRRK2/G2019S LRRK2 respectively. | ||||||||||
Targets |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 32.75 mL | 163.76 mL | 327.51mL |
| 0.5 mM | 6.55 mL | 32.75 mL | 65.5 mL |
| 1 mM | 3.28 mL | 16.38 mL | 32.75 mL |
| 5 mM | 0.66 mL | 3.28 mL | 6.55 mL |
*The above data is based on the productmolecular weight 305.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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