PF-06835375 is a humanized IgG1 antibody targeting CXCR5, which is predominantly expressed on B cells, T follicular helper (Tfh) cells, and circulating Tfh-like (cTfh) cells. This antibody is useful for investigating the pathophysiology of systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). Its specificity for CXCR5 makes it a valuable tool in studies focused on immune response and B-cell development in autoimmune diseases.
PF-06835375 is a humanized IgG1 antibody targeting CXCR5, which is predominantly expressed on B cells, T follicular helper (Tfh) cells, and circulating Tfh-like (cTfh) cells. This antibody is useful for investigating the pathophysiology of systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). Its specificity for CXCR5 makes it a valuable tool in studies focused on immune response and B-cell development in autoimmune diseases.
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