Catalog No.: A11527
Autotaxin inhibitor
PF-8380 is a potent and specific autotaxin inhibitor with an IC50 value of 2.8 nM.
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Product Name Price Stock Qty
PF-8380 5mg
In stock
PF-8380 10mg
In stock
PF-8380 25mg
In stock

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Biological Activity
Discription PF-8380 is a potent and specific autotaxin inhibitor with an IC50 value of 2.8 nM.
Target Value
Chemical Information
Catalog Num A11527
Formula C22H21Cl2N3O5
Molecular Weight 478.33
CAS Number 1144035-53-9
Synonyms PF 8380, PF8380

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

In vitro (25°C) DMSO 89 mg/mL (186.06 mM)
Water Insoluble
Ethanol Insoluble
In vivo 1%cmc-na 14 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.91 mL 104.53 mL 209.06 mL
0.5 mM 4.18 mL 20.91 mL 41.81 mL
1 mM 2.09 mL 10.45 mL 20.91 mL
5 mM 0.42 mL 2.09 mL 4.18 mL
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