Phenylaminojuglone AJ-2 is a potent nitric oxide synthase inhibitor that modulates various targets, including soluble guanylate cyclase and calcium channels. It effectively blocks extracellular Ca2+ influx, thereby regulating the NO-sGC-cGMP signaling pathway and inhibiting both pharmacological and electromechanical contractions of smooth muscle. This compound is particularly relevant for research investigating intestinal spasm and related gastrointestinal disorders.
Phenylaminojuglone AJ-2 is a potent nitric oxide synthase inhibitor that modulates various targets, including soluble guanylate cyclase and calcium channels. It effectively blocks extracellular Ca2+ influx, thereby regulating the NO-sGC-cGMP signaling pathway and inhibiting both pharmacological and electromechanical contractions of smooth muscle. This compound is particularly relevant for research investigating intestinal spasm and related gastrointestinal disorders.
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