Phosphocreatine dipotassium is an endogenous metabolite that serves as a critical energy reservoir in vertebrate skeletal muscles. It enhances antioxidant activity and activates the TAK1 pathway, providing cardioprotective effects. Furthermore, phosphocreatine normalizes mitochondrial function and mitigates oxidative stress via the Akt-mediated Nrf2/HO-1 pathway. It also offers renal protection by suppressing apoptosis and reactive oxygen species generation through the ERK-mediated Nrf2/HO-1 pathway, making it a valuable reagent for studies in cellular metabolism and oxidative stress.
Phosphocreatine dipotassium is an endogenous metabolite that serves as a critical energy reservoir in vertebrate skeletal muscles. It enhances antioxidant activity and activates the TAK1 pathway, providing cardioprotective effects. Furthermore, phosphocreatine normalizes mitochondrial function and mitigates oxidative stress via the Akt-mediated Nrf2/HO-1 pathway. It also offers renal protection by suppressing apoptosis and reactive oxygen species generation through the ERK-mediated Nrf2/HO-1 pathway, making it a valuable reagent for studies in cellular metabolism and oxidative stress.
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