Pim-1 kinase inhibitor 8 is a selective inhibitor of the PIM-1 kinase, exhibiting an IC50 value of 14.3 nM. This compound effectively disrupts cellular proliferation and migration by inhibiting PIM-1, leading to the induction of apoptosis and autophagy. In vivo studies demonstrate its capability to inhibit solid tumor growth in Solid Ehrlich Carcinoma (SEC)-bearing mice. Pim-1 kinase inhibitor 8 is valuable for research focused on breast and liver cancer.
Pim-1 kinase inhibitor 8 is a selective inhibitor of the PIM-1 kinase, exhibiting an IC50 value of 14.3 nM. This compound effectively disrupts cellular proliferation and migration by inhibiting PIM-1, leading to the induction of apoptosis and autophagy. In vivo studies demonstrate its capability to inhibit solid tumor growth in Solid Ehrlich Carcinoma (SEC)-bearing mice. Pim-1 kinase inhibitor 8 is valuable for research focused on breast and liver cancer.
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