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Pip-alkyne-Ph-COOCH3

PROTAC Linkers

Pip-alkyne-Ph-COOCH3 is a versatile PROTAC linker designed for the synthesis of PROTAC ARD-266. This compound features an alkyne group, facilitating its use in click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc). It plays a critical role in forming stable linkages between target proteins and E3 ligases, supporting research in targeted protein degradation and related therapeutic applications.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2308496-47-9
Applications	PROTAC Linkers
Formula	C₁₅H₁₇NO₂
Molecular Weight	243.30
SMILES	O=C(OC)C1=CC=C(C#CC2CCNCC2)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.